'Even if research has been carried out, it's usually only one or two small studies, the results of which haven't been repeated or seen in larger studies.' Many over-the-counter slimming tablets also provide very little information on the packaging, often even failing to provide basic facts on how the product supposedly works to aid weight loss. She says, 'Many clinical trials have looked at the efficacy of Xenical and Reductil in the treatment of obesity and found them to successfully help obese people lose weight.' But like many health professionals, Carey believes their success in treating obesity isn't just the result of their active ingredients, but is also due to the lifestyle advice that patients receive. But do slimming pills really work? ! ? Bear in mind, too, that while some of these tablets may claim to be supported by research, this is likely to be a 'one-off' small study. They receive diet and exercise advice and get plenty of support to help them along the way,' Carey explains. but probably not the right sort! ! ? Fail to come with dietary advice ? If you concentrate on making long-term changes to your diet and lifestyle, you won't need to resort to quick fix remedies. Most over-the-counter pills are extremely expensive, too, with the result that you can be sure you'll lose pounds ? In contrast, Reductil enhances satiety by indirectly boosting levels of serotonin, a chemical that helps you feel full. This means they're not allowed to make certain claims such as ?speeds up metabolism? Currently in the UK, there are only two anti-obesity drugs available on prescription ? Some may also interact with other medications.